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Tom Russell, Ting Xu publish in Nature

Near Complete Depolymerization Of Polyesters With Nano-Dispersed Enzymes was recently published in Nature. By nanoscopically dispersing enzymes with deep active sites, Xu, Russell and coworkers have degraded semi-crystalline polyesters primarily via chain-end mediated processive depolymerization with programmable latency and material integrity, akin to polyadenylation-induced mRNA decay.

Image Schematic of nanoscopically confined enzyme degrading a semi-crystalline polymer by a processive depolymerization to monomer.

DelRe, et al., Nature (2021) https://dx.doi.org/10.1038/s41586-021-03408-3

UMass News Office

April 22, 2021