Tew Research Group

Publications

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176. K. R. McLeod, G. N. Tew, “Microphase-Separated Thiol-Ene Co-Networks from Telechelic Macromonomers with Asymmetric Molecular Weights,” Macromolecules, 50, 8042-8047, (2017), DOI: 10.1021/acs.macromol.7b10681.


175. J. M. Sarapas, C. M. Backlund, B. M. deRonde, L. M. Minter, G. N. Tew, “ROMP- and RAFT-Based Guanidinium-Containing Polymers as Scaffolds for Protein Mimic Synthesis,” Chem. Eur. J.,  23, 6858-6863, (2017), DOI: 10.1002/chem.201700423, PMCID: PMC5551038, PMID: 28370636.​

174. R. W. Scott, G. N. Tew, “Mimics of Host Defense Proteins; Strategies for Translation to Therapeutic Applications,” Curr. Top. Med. Chem., 17, 576-589, (2017), DOI: 10.2174/1568026616666160713130452.

173. F. Sgolastra, C. M. Backlund, E. I. Ozay, B. M. deRonde, L. M. Minter, G. N. Tew, “Sequence Segretation Improves Non-Covalent Protein Delivery,” J. Con. Rel., 254, 131-136, (2017), DOI: 10.1016/jconrel.2017.03.387.

172. A. O. Tezgel, P. Jacobs, C. M. Backlund, J. C. Telfer, G. N. Tew, “Synthetic Protein Mimics for Functional Protein Delivery,” Biomacromolecules, 18, 819-825, (2017), DOI: 10.1021/acs.biomac.6b01685.

171. M. Kwasny, G. N. Tew, “Expanding Metal Cation Options in Polymeric Anion Exchange Membranes,” J. Mat. Chem. A5, 1400-1405, (2017), DOI: 10.1039/C6TA07990C.

170. C. Backlund, F. Sgolastra, R. Otter, L. M. Minter, T. Takeuchi, S. Futaki, G. N. Tew, “Increased Hydrophobic Block Length of PTDMs Promotes Protein Internalization,” Polym. Chem., 7, 7514-7521, (2016), DOI: 10.1039/C6PY01615D.

169. J. M. Sarapas, G. N. Tew, “Thiol-ene Step-Growth as a Versatile Route to Functional Polymers,” Angew. Chem. Intl. Ed., 55, 15860-15863, (2016), DOI: 10.1002/anie.201609023.

  

168. N. D. Posey, L. Caffrey, L. M. Minter, G. N. Tew, “Protein Mimic Hydrophobicity Affects Intracellular Delivery but not Cargo Binding,” Chemistry Select., 1, 6146-6150, (2016), DOI: 10.1002/slct.201601652.

167. E. I. Ozay, G. Gonzalez-Perez, J. A. Torres, J. Vijayaraghavan, R. Lawlor, H. L. Sherman, D. T. Jr., Garrian, A. S. Burnside, B. A. Osborne, G. N. Tew, L. M. Minter, “Intracellular Delivery of Anti-pPKCθ (Thr538) via Protein Transduction Domain Mimics for Immunomodulation,” Mol. Ther., 111-111, (2016), DOI: 10.1038/mt.2016.177, PMID: 27633441.

166. L. M. Caffrey, B. M. deRonde, L.. M. Minter, G. N. Tew, "Mapping Optimal Charge Density and Length of ROMP-Based PTDMs for siRNA Internalization," Biomacromolecules​, 17, 3205-3212, (2016), DOI: 10.1021/acs.biomac.6b00900, PMID: 27599388, PubMed in process.

165. M. Lis, F. Dorner, G. N. Tew, K. Lienkamp, “Anionic Lipid Content Presents a Barrier to ROMP-based PTDM Activity,” Langmuir, 32, 5946-5954, (2016), DOI: 10.1021/acs.langmuir.6b00230, PMID: 27182863.

164. B. deRonde, N. Posey, R. Otter, L. M. Minter, G. N. Tew, “Optimal Hydrophobicity in ROMP-based Protein Mimics Required for siRNA Internalization,” Biomacromol., 17, 1969-1977, (2016), DOI: 10.1021/acs.biomac.6b00138.

163. J. Sarapas, K. Saijo, Y. Zhao, M. Takenaka, G. N. Tew, "Phase Behavior and Li+ Ion Conductivity of Styrene-Ethylene Oxide Multiblock Copolymer Electrolytes," Polym. Adv. Technol., 27, 946-954, (2016), DOI: 10.1002/pat.3753.

162. J. Sarapas, G. N. Tew, “Poly(ether-thioethers) by Thiol-ene click and their Oxidized Analogues as Lithium Polymer Electrolytes,” Macromol., 49, 1154-1162, (2016), DOI: 10.1021/acs.macromol.5b02513.

161. C. Backlund, T. Takeuchi, S. Futaki, G. N. Tew, “Relating Structure and Internalization for ROMP-based Protein Mimics,” Biochim Biophys Acta., 1858, 1443-1450, (2016), DOI: 10.1016/j.bbamem.2016.03.024, PMID: 27039278.


160. M. Khan, J. Yang, C. C. Shi, Y. K. Feng, W. C. Zhang, K. Gibney, G. N. Tew, Surface Modification of Polycarbonate Urethane with Zwitterionic Polynorbornene via Thiol-ene Click-Reaction to Facilitate Cell Growth and Proliferation,” Macromol Mtrls Eng, 300, 802-809, (2015), DOI: 10.1002/mame.201500038.

159. B. deRonde, J. Torres, L. Minter, G. N. Tew, "Development of Guanidinium-rich Protein Mimics for Efficient siRNA Delivery into Human T Cells," Biomacromol., 16, 3172-3179,  (2015), DOI: 10.1021/acs.biomac.5b00795, PMID: 26324222.

158. M. Lein, B. M. deRonde, F. Sgolastra, G. N. Tew, M. A. Holden, "Protein Transport Across Membranes: Comparison Between Lysine and Guanidine-rich Carriers," Biochim Biophys Acta, 1848, 2980-2984, (2015), DOI: 10.1016/j.bbamem.2015.09.004, PMID: 26342679. 


157. B. deRonde, G. N. Tew, "Development of Protein Mimics for Intracellular Delivery," Biopolymers, 104, 265-280, (2015), DOI: 10.1002/bip.22658. 

156.. M. Khan, J. Yang, C. Shi, Y. Feng, W. Zhang, K. Gibney, G. N. Tew, "Manipulation of Polycarbonate Urethane Bulk Properties via Incorporated Zwitterionic Polynorbornene for Tissue Engineering Applications," RSC Adv., 5, 11284-11292, (2015), DOI: 10.1039/c4ra14608e.

 

155. B. deRonde, A. Birke, G. N. Tew, "Design of Aromatic-containing Cell Penetrating Peptide Mimics with Structurally Modified π-electronics," Chem. Eur. J., 21, 3013-3013, (2015), DOI: 10.1002/chem.201405381.

 

154. *K. Zhang, G. N. Tew, "Cyclic Polymers as a Building Block for Cyclic Brush  Polymers and Gels," Reactive & Func. Polym., 80, 40-47, (2014), DOI: 10.1016/j.reactfunctpolym.2014.01.012.

 

153. C. N. Walker, K. C. Bryson, R. C. Hayward, G. N. Tew, "Wide Bicontinuous Compositional Windows from Co-networks Made with Telechelic Macromonomers," ACS Nano, 8, 12376-12385, (2014), DOI: 10.1021/nn505026a.

    

152. *C. N. Walker, J. M. Sarapas, V. Kung, A. L. Hall, G. N. Tew, "Multiblock Copolymers by Thiol Addition Across Norbornene," ACS Macro Letts., 3, 453-457, (2014), DOI: 10.1021/mz5001288.

    

151. F. Sgolastra, L. M. Minter, B. A. Osborne,, G. N. Tew, "The Importance of Sequence Specific Hydrophobicity in Synthetic Protein Transduction Domain Mimics," Biomacromolecules, 15, 812-820, (2014), DOI: 10.1021/bm401634r. 

150. E. M. Saffer, M. A. Lackey, D. M. Griffin, S. Kishore, G. N. Tew, S. R. Bhatia, "SANS Study of Highly Resilient Poly(ethylene glycol) Hydrogels," Soft Matter, 10, 1905-1916, (2014), DOI: 10.1039/c3sm52395k. 

149. C. Leng, K. A. Gibney, Y. Liu, G. N. Tew, Z. Chen, "In Situ Probing the Surface Restructuring of Antibiofouling Amphiphilic Polybetaines in Water," ACS Macro Lett.2, 1011-1015, (2013), DOI: 10.1021/mz400503z.

148. M. L. Disabb-Miller, Y. Zha, A. J. DeCarlo, M. Pawar, G. N. Tew, M. A. Hickner, "Water Uptake and Ion Mobility in Cross-linked Bis(terpyridine) Ruthenium-based Anion Exchange Membranes," Macromolecules46, 9279-9287, (2013), DOI: 10.1021/ma401701n. 

        

147. K. Zhang, Y. Zha, B. Peng, Y. Chen, G. N. Tew, "Metallo-Supramolecular Cyclic Polymers," J. Am. Chem. Soc.135, 15994-15997, (2013), DOI: 10.1021/ja407381f.

 

146. D. T. Martin, C. J. Holmes, H. Z. Kaimakliotis, C. J. Cheng, K. Zhang, J. Liu, M. A. Wheeler, W. K. Kelly, G. N. Tew, W. M. Saltzman, R. M. Weiss, "Nanoparticles for Urothelium Penetration and Delivery of the Histone Deacetylase Inhibitor Belinostat for Treatment of Bladder Cancer,"Nanomed: NBM9, 1124-1134, (2013). DOI: 10.1016/j.nano.2013.05.017, PCMID: PMC3815967 

145. *F. Sgloastra, B. deRonde, J. M. Sarapas, A. Som, G. N. Tew, "Designing Mimics of Membrane Active Proteins," Acct. Chem. Res., 46, 2977-2987, (2013), DOI: 101021/ar400066v, PMCID-in process. 

144. T.- H. Fu, Y. Li. H. D. Thaker, R. W. Scott, G. N. Tew, "Expedient Synthesis of SMAMPs via Click Chemistry," ACS Med. Chem. Lett., 4, 841-845, (2013), DOI: 10.1021/ml400155a. 

 

143. H. D. Thaker, A. Cankaya, R. W. Scott, G. N. Tew, "Role of Amphiphilicity in the Design of Synthetic Mimics of Antimicrobial Peptides with Gram-Negative Activity," ACS Med. Chem. Lett.4, 481-485, (2013), DOI:10.1021/ml300307b . 

 

142. A. O. Tezgel, G. Gonzalez-Perez, J. C. Telfer, B. A. Osborne, L. M. Minter, G. N. Tew,"Novel Protein Transduction Domain Mimics as Nonviral Delivery Vectors for siRNA Targeting NOTCH1 in Primary Human T Cells," Mol. Ther., 21, 201-209, (2013), DOI: 10.1038/mt.2012.209. 

  

141.  Y. Zha, R. R. Maddikeri, S. P. Gido, M. T. Tuominen, G. N. Tew,"Magnetic Properties of Cobalt-Containing Diblock Copolymers with Cylindrical Morphology of Different Domain Sizes," J. Inorg. Organomet. Polym.23, 89-94, (2013), DOI:10.1007/s10904-012-9744-2.

                                                                                    

140. N. Schmidt, M. Lis, A. Anastassia, K. Zhao, G. Lai, G. N. Tew, G. Wong, "Molecular Basis for Nanoscopic Membrane Curvature Generation from Quantum Mechanical Models and Synthetic Transporter Sequences," J. Am. Chem. Soc. 46, 19207-19216, (2012), DOI: 10.1021/ja308459j. 

 

139. Y. Zha, H. D. Thaker, R. R. Maddikeri, S. P. Gido, M. T. Tuimonen, G. N. Tew, "Nanostructured Block-Random Copolymers with Tunable Magnetic Properties," J. Am. Chem. Soc., 134, 14534-14541, (2012). 

138. A. Som, N. Navasa, A. Percher, R. W. Scott, G. N. Tew, J. Anguita, "Identification of Synthetic Host Defense Peptide Mimics that Exert Dual Antimicrobial and Anti-Inflammatory Activities," Clinical & Vaccine Immun., 19, 1784-1971, (2012), DOI: 10.1128/CVI.00291-12. 

137. Y. Li, K.-N. Kumar, J. M. Dabkowski, M. Corrigan, R. W. Scott, K. Nusslein, G. N. Tew, "A New Bactericidal Surgical Suture Coating," Langmuir28, 12134-12139, (2012), DOI: 10.1021/la302732w. 

136. J. Cui, M. Lackey, G. N. Tew, A. J. Crosby, "Mechanical Properties of End-linked PEG/PDMS Hydrogels," Macromolecules45, 6104-6110, (2012), DOI: 10.1021/ma300593g. 

  

135. H. D. Thaker, A. Som, F. Ayaz, R.W. Scott, J. Anguita, G. N. Tew, "Synthetic Mimics of Antimicrobial Peptides with Immunomodulatory Responses," J. Am. Chem. Soc.134, 11088-11091, (2012), DOI: 10.1021/ja303304j. 

 

134. *C. N. Walker, C. Versek, M. Tuominen, G. N. Tew, "Tunable Networks from Thiol-ene Chemistry for Lithium Ion Conduction," ACS Macro Lett.1, 737-741, (2012), DOI: 10.1021/mz300090m. 

133. S. Colak, G. N. Tew,"Amphiphilic Polybetaines: the Effect of Side-chain Hydrophobicity on Protein Adsorption," Biomacromolecules13, 1233-1239, (2012), DOI: 10.1021/bm201791p. 

132. A. Som, Y. Xu, R. W. Scott, G. N. Tew, "Anion Mediated Activation of Guanidine Rich Small Molecules," Org. & Biomol. Chem.10, 40-42, (2012), DOI: 10.1039/CIOB06373A. 

131. A. Som, A. Reuter, G. N. Tew, "Protein Transduction Domain Mimics: The Role of Aromatic Functionality," Angew. Chem. Int. Ed.51, 980-983, (2012), DOI: 10.1002/anie.201104624. 

 

130. K. Zhang, G. N. Tew, "Cyclic Brush Polymers by Combining Ring-Expansion Metathesis Polymerization and the 'Grafting from' Technique," ACS Macro Letters1, 574-579, (2012), DOI: 10.1021/mz2001675. 

129. J. Cui, M. A. Lackey, A. E.  Madkour, E. M. Saffer, D. M. Griffin, S. R. Bhatia, A. J. Crosby, G. N. Tew, "Synthetically Simple, Highly Resistant Hydrogels," Biomacromolecules13, 584-588, (2012), DOI: 10.1021/bm300015s. 

 

128. Y. Zha, M. L. Disabb-Miller, Z. D. Johnson, M. A. Hickner, G. N. Tew "Metal Cation-Based Anion Exchange Membranes", JACS134, 4493-4496, (2012), DOI: 10.1021/ja211365r. 

 

127. S. Colak, G. N. Tew, "Dual-Functional ROMP-Based Betaines: Effect of Hydrophilicity and Backbone Stucture on Non-Fouling Properties", Langmuir28, 666-675 (2012), DOI: 10.1021/la203683u. 

126. E. M. Saffer, G. N. Tew, S. R. Bhatia, "Poly(lactic acid)-poly(ethylene oxide) Block Copolymers: New Directions in Self-Assembly and Biomedical Applications," Cur. Med. Chem.18, 5676-5686, (2011), DOI: 10.2174/092986711798347324. 

125. Z. M. AL-Badri, R. R. Maddikeri, Y. Zha, H. D. Thaker, P. Dobriyal, R. Shunmuam, T. P. Russell, G. N. Tew, "Room Temperature Magnetic Materials from Nanostructured Diblock Copolymers," Nature Comms.2, 482, (2011), DOI: 10.1038/ncomms1485. 

 

124. R. R. Maddikeri, S. Colak. S. P. Gido, G. N. Tew, "Zwitterionic Polymersomes in an Ionic Liquid: Room Temperature TEM Characterization," Biomacromolecules12, 3412-3417, (2011), DOI: 10.1021/bm2010142. 

123. J. M. Rathfon, R. W. Cohn, A. J. Crosby, J. P. Rothstein, G. N. Tew, "Confinement Effects on Chain Entanglement in Free-Standing Polystyrene Ultrathin Films,"  Macromolecules44, 5436-5442, (2011), DOI: 10.1021/ma1026324. 

 

122. A. O. Tezgel, J. C. Telfer, G. N. Tew, "DeNovo Designed Protein Transduction Domain Mimics from Simply Synthetic Polymers," Biomacromolecules12, 3078-3083, (2011), DOI: 10.1021/bm200694u. 

121. W. Hu, A. Som, G. N. Tew, "Interaction Between Lipids and Antimicrobial Oligomers Studied by Solid-State NMR," J. Phys. Chem. B.115, 8474-8480, (2011), DOI: 10.1021/jp202414m. 

  

120. K. Zhang, M. A. Lackey, Y. Wu, G. N. Tew, "Universal Cyclic Polymer Templates," J. Am. Chem. Soc.133, 6906-6909, (2011), DOI: 10.1021/ja2007559. 

119. A. Som, A. O. Tezgel, G. J. Gabriel, G. N. Tew, "Self Activation in De Novo Designed Mimics of Cell-Penetrating Peptides," Angew Chem., Int. Ed.50, 6147-6150, (2011), DOI:10.1002/anie.201101535 . 

118. K. Lienkamp, A. E. Madkour, G. N. Tew, "Antibacterial Peptidomimetics: Polymeric Synthetic Mimics of Antimicrobial Peptides," Adv. Polym. Sci., 1-32, (2011), DOI: 10.1007/12_2010_85.  

117. K. Zhang, M. Lackey, J. Cui, G. N. Tew, "Gels Based on Cyclic Polymers,"J. Am. Chem. Soc.,133, 4140-4148, (2011), DOI: 10.1021/ja111391z. 

116.  H. D. Thaker, F. Sgolastra, D. Clements, R. Scott, G. N. Tew, "Synthetic Mimics of Antimicrobial Peptides from Triaryl Scaffolds," J. Med. Chem.54, 2241-2254, (2011), DOI: 10.1021/jm101410t. 

115.  A. E. Madkour, J. M. Grolman, G. N. Tew, "Synthesis of Hydrogels via Ring-Opening Metathesis Polymerization: Factors Affecting Gelation," Polym. Chem.2, 114-119, (2011), DOI: 10.1039/C0PY00151A. 

114.  K. Zhang, J. Cui, M. Lackey, G. N. Tew, "Hydrogels Based on Living Ring-Opening Metathesis Polymerization," Macromolecules43, 10246-10252, (2010).

 

113.  J. M. Rathfon, R. W. Cohn, A. J. Crosby, G. N. Tew, "Hole Nucleation in Free-standing Polystyrene Ultra-thin Films", Macromolecules44, 134-139, (2010). 

112.  S. K. Agrawal, N. Sanabria-DeLong, S. K. Bhatia, G. N. Tew, "Energetics of Association in Poly(lactic acid)-based Hydrogels with Crystalline and Nanoparticle-Polymer Junctions," Langmuir26, 17330-17338, (2010). 

111.  R. Shunmugam, G. J. Gabriel, K. A. Aamer, G. N. Tew, “Metal-Ligand Containing Polymers: Terpyridine as the Supramolecular Unit,” Macromol. Rapid Comm.31, 784-793, (2010). 

110.  A. E. Madkour, A. H. R. Koch, K. Lienkamp, G. N. Tew, “End-Functionalized ROMP Polymers for Biomedical Applications,” Macromolecules43, 4557-4561, (2010). 

109. J. Jiang, M. M. Slutsky, T. V. Jones, G. N. Tew, “Apolar ortho-Phenylene Ethynylene Oligomers: Conformational Ordering without Intermolecular Aggregation,” New J. Chem.34, 307-312, (2010). 

108. G. N. Tew, R. W. Scott, M. L. Klein, W. F. DeGrado, “De Novo Design of Antimicrobial Polymers, Foldamers, and Small Molecules: From Discovery to Practical Applications,” Acc. Chem. Res.43, 30-39, (2010).

107.  J. A. Lamboy, J. A. Arter, K. A. Knopp, D. Der, C. M. Overstreet, E. F. Palermo, H. Urakami, T.-B. Yu, O. Tezgel, G. N. Tew, Z. B. Guan, K. Kuroda, G. A. Weiss, “Phage Wrapping with Cationic Polymers Eliminates Nonspecific Binding between M13 Phage and High p/Target Proteins,” J. Am. Chem. Soc131, 16454-16460, (2009). 

106. K. Lienkamp, A. E. Madkour, K.-N. Kumar, Klaus Nüsslein, G. N. Tew, "Antimicrobial Polymers Prepared by Ring-Opening Metathesis Polymerization: Manipulating Antimicrobial Properties by Organic Counterion and Charge Density Variation,” Chem. E. J.15, 11715-11722, (2009). 

105. K. Lienkamp, K.-N. Kumar, A. Som, K. Nüsslein, G. N. Tew, “’Doubly Selective Antimicrobial Polymers: How Do They Differentiate Between Bacteria?” Chem. E. J.15, 11710-11714, (2009). PDF

104. A. Som, L. Yang, G. Wong, G. N. Tew, “Divalent Metal Ion Triggered Activity of a Synthetic Antimicrobial in Cardiolpin Membranes,” J. Am. Chem. Soc., 131, 15102-15103, (2009). PDF

103. K. Lienkamp, G. N. Tew, “Synthetic Mimics of Antimicrobial Peptides – A Versatile Ring-Opening Metathesis Polymerization Based Platform for the Synthesis of Selective Antibacterial and Cell-Penetrating Polymers,” Chem. E. J., 15, 11784-11800, (2009).*Highlighted on the Cover. PDF

102. C. W. Avery, A. Som, Y. Xu, G. N. Tew, Z. Chen, “Dependence of Antimicrobial Selectivity and Potency on Oligomer Structure Investigated Using Substrate Supported Lipid Bilayers and Sum Frequency Generation Vibrational Spectroscopy,” Anal. Chem.81, 8365-8372, (2009).

101. J. M. Rathfon, J. M. Grolman, A. J. Crosby, G. N. Tew, "Formation of Oriented, Suspended Fibers by Melting Free Standing Polystyrene Thin Films,” Macromolecules42, 6716-6722, (2009).

100. S. Pabba, M. M. Yazdanpanah, B. H. F. Totten, W. Dobrokhotov, J. M. Rathfon, G. N. Tew, R. Cohn, “Biopolymerization-Driven Self-Assembly of Nanofiber Air-Bridges,” Soft Matter5, 1378-1385, (2009). 

99. *T. Eren, G. N. Tew, “Phosphonic Acid Based Amphiphilic Diblock Copolymers Derived from ROMP,” Journal of Poly. Sci. Poly. Chem.47, 3949-3956, (2009). 

98. J. Chen, J. A. Hessler, K. Putchakayala, B. K. Panama, D. P. Khan, S. Hong, D. G. Mullen, S. C. DiMaggio, A. Som, G. N. Tew, A. N. Lopatin, J. R. Baker, Jr., M. M. Banaszak Holl, B. G. Orr, “Cationic Nanoparticles Induce Nanoscale Disruption in Living Cell Plasma Membranes,” J. Phys. Chem.113, 11179-11185, (2009).    

97. K. Lienkamp, C. F. Kins, S. F. Alfred, A. E. Madkour, G. N. Tew, “Water-Soluble Polymers from Acid-Functionalized Norbornenes,” Jrnl. Polym. Sci, Polym. Chem.47, 1266-1273, (2009). 

96.  S. Colak, C. F. Nelson, K. Nüsslein, G. N. Tew, "Hydrophilic Modifications on an Amphiphilic Polynorbornene and the Effects on its Hemolytic and Antibacterial Activity," Biomacromolecules10, 353-359, (2009). 

95. J. M. Rathfon, Z. M. AL-Badri, R. Shunmugam, S. M. Berry, S. Pabba, R. S. Keynton, R. W. Cohn, G. N. Tew, “Fluorimetric Nerve Gas Sensing Based on Pyrene Imines Incorporated into Films and Sub-Micrometer Fibers,” Adv. Funct. Mat.19, 689-695, (2009). 

94. A. E. Madkour, J. M. Dabkowski, K. Nüsslein, G. N. Tew, "Fast Disinfecting Antimicrobial Surfaces," Langmuir25, 1060-1067, (2009). 

 93. G. J. Gabriel, J. A. Maegerlein, C. F. Nelson, J. M. Dabkowski, T. Eren, K. Nüsslein, G. N. Tew, “Comparison of Facially Amphiphilic versus Segregated Monomers in the Design of Antibacterial Copolymers.” Chem. Eur. J.15, 433-439, (2009). PDF

 

92. L. Yang, V. D. Gordon, D. R. Trinkle, N. W. Schmidt, M. A. Davis, C. DeVries, A. Som, J. E. Cronan, Jr., G. N. Tew, G. C. L. Wong, “Mechanism of a Prototypical Synthetic Membrane-Active Antimicrobial: Efficient Hole-Punching via Interaction with Negative Intrinsic Curvature Lipids,” Proc. Natl. Acad. Sci., 105, 20595-20600, (2008). PDF

 

91. R. W. Scott, W. F. DeGrado, G. N. Tew, “De Novo Designed Synthetic Mimics of Antimicrobial Peptides,” Cur. Opin. BioTech.19, 620-627, (2008). PDF

 

90. Z. M. AL-Badri, A. Som, S. Lyon, C. F. Nelson, K. Nüsslein, G. N. Tew, “Investigating the Effect of Increasing Charge Density on the Hemolytic Activity of Synthetic Antimicrobial Polymers,” Biomacromolecules9, 2805-2810, (2008). PDF

 

89. G. J. Gabriel, A. E. Madkour, J. M. Dabkowski, C. F. Nelson, K. Nüsslein, G. N. Tew, “Synthetic Mimic of Antimicrobial Peptide with Nonmembrane-Disrupting Antibacterial Properties,” Biomacromolecules9, 2980-2983, (2008). PDF

 

88. S. K. Agrawal, N. Sanabria-DeLong, G. N. Tew, S. R. Bhatia, “Nanoparticle-Reinforced Associative Network Hydrogels,” Langmuir24, 13148-13154, (2008). PDF     

 

87. S. Colak, G. N. Tew, “Synthesis and Solution Properties of Norbornene Based Polybetaines,” Macromolecules41, 8436-8440, (2008). PDF

 

86. S. K. Agrawal, N. Sanabria-DeLong, G. N. Tew, S. R. Bhatia, “Structural Characterization of PLA-PEO-PLA Solutions and Hydrogels: Crystalline vs. Amorphous PLA Domains,” Macromolecules41, 1774-1784, (2008). PDF

 

85. M. M. Slutsky, J. S. Phillip, G. N. Tew, “Synthesis and Characterization of Amphiphilic o-Phenylene Ethynylene Oligomers,” New J. Chem.4, 557-744, (2008). PDF

 

84. N. Sanabria-DeLong, A. J. Crosby, G. N. Tew,“Photo-Cross-Linked PLA-PEO-PLA Hydrogels from Self-Assembled Physical Networks: Mechanical Properties and Influence of Assumed Constitutive Relationships,” Biomacromolecules9, 2784-2791, (2008). PDF

 

83. G. J. Gabriel, J. Pool, A. Som, J. M. Dabkowski, E. B. Coughlin, M. Muthukumar, G. N. Tew, “Interactions Between Antimicrobial Polynorbornenes and Phospholipid Vesicles Monitored by Light Scattering and Microcalorimetry,” Langmuir24, 12489-12495, (2008). PDF

 

82. J. Jiang, G. N. Tew, "Synthesis of Macrocycle Isomers via Metathesis Cyclization and Their Self-Assembly from Aqueous Solutions," Org. Lett., 10, 4393-4396, (2008). PDF

 

81. S. F. Alfred, K. Lienkamp, A. E. Madkour, G. N. Tew, "Water-Soluble ROMP Polymers from Amine-Functionalized Norbornenes," J. Polym. Sci. Part A: Polym. Chem., 46, 6672-6676, (2008). PDF

 

80. K. Liamp, A. E. Madkour, A. Musante, C. F. Nelson, K. Nüsslein, G. N. Tew, “Antimicrobial Polymers Prepared by ROMP with Unprecedented Selectivity: A Molecular Construction Kit Approach,” J. Am. Chem. Soc.136, 9836-9843 (2008). PDF

 

79. T. V. Jones, M. M. Slutsky, G. N. Tew, “Extending Helicity-Capturing the Helical Character of Longer ortho-Phenylene Ethynylene Oligomers,” New J. Chem.32, 676-679, (2008).  Highlighted on the Cover. PDF

 

78. R. Shunmugam, G. N. Tew, “Terpyridine-Lanthanide Complexes Respond to Fluorophosphate Containing Nerve Gas G-Agent Surrogates,” Chem. Eur. J, 14, 5409-5412(2008).  PDF

 

77. R. Shunmugam, G. N. Tew, “Polymers that Contain Ligated Metals in their Side Chain: Building a Foundation for Functional Materials in Opto-Electronic Applications with an Emphasis on Lanthanide Ions,” Macrol. Rapid Comm., 29, 1355-1362, (2008).  Feature Article: Highlighted on the Cover ( with an acknowledgement to Dr. Morris Slutsky for assistance with the cover image).  PDF

 

76. A. Hennig, G. J. Gabriel, G. N. Tew, S. Matile, "Stimuli-Responsive Polyguanidino-Oxanorbornene Membrane Transporters as Multicomponent Sensors in Complex Matrices," J. Am. Chem. Soc., 130, 10338-10344. (2008). PDF

 

75. Z. AL-Badri, G. N. Tew, "Well-Defined Acetylene-Functionalized Oxanorbornene Polymers and Block Copolymers," Macromolecules, 41, 4173-4179, (2008). PDF

 

74. J. M. Rathfon, G. N. Tew, “Synthesis of Thermoresponsive Poly(N-Isopropylmethacrylamide) and Poly(Acrylic Acid) Block Copolymers via Post-Functionalization of Poly(N-Methacryloxysuccinimide),” Polymer, 49, 1761-1769. (2008). PDF

 

73. S. F. Alfred, Z. M. AL-Badri, A. E. Madkour, K. Lienkamp, G. N. Tew, "Water Soluble Poly(ethylene oxide) Functionalized Norbornene Polymers," J. Polym. Sci: Part A: Polym. Chem., 46, 2640-2648, (2008). PDF

 

72. R. Shunmugam, G. N. Tew, "White Light Emission from Mixing Blue and Red-Emitting Metal Complexes," Polym. Adv. Tech., 19, 1-5, (2008). PDF

 

71. R. Shunmugam, G. J. Gabriel, C. E. Smith, K. A. Aamer, G. N. Tew, "A Highly Selective Colorimetric Aqueous Sensor for Mercury," Chem. Eur. J., 14, 3904-3907, (2008). PDF

 

70. A. Som, G. N. Tew, "Influence of Lipid Composition on Membrane Activty of Antimicrobial Phenylene Ethynylene Oligomers," J. Phys. Chem. B., 112, 3495-3502, (2008). PDF

 

69. T. Eren, A. Som, J. R. Rennie, C. F. Nelson, Y. Urgina, K. Nusslein, E. B. Coughlin, G. N. Tew, "Antibacterial and Hemolytic Activities of Quaternary Pyridinium Functionalized Polynorbornenes," Macomol. Chem. Phys., 209, 516-524, (2008). PDF

 

68. A. Som, S. Vemparala,  I. Ivanov, G. N. Tew, "Synthetic Mimics of Antimicrobial Peptides," Biopolymers, 90, 83-93, (2008). PDF

 

67. K. A. Aamer, W. H. de Jeu, G. N. Tew, "Diblock Copolymers Containing Metal Complexes in the Side Chain of One Block,Macromolecules, 41, 2022-2029, (2008). PDF

 

66. G. J. Gabriel, G. N. Tew, "Conformationally Rigid Proteomimetics: A Case Study in Designing Antimicrobial Aryl Oligomers," Org. Biomol. Chem., 6, 417-423, (2008). PDF

 

65. A. E. Madkour, G. N. Tew, "Toward Self-Sterilizing Medical Devices: Controlling Infection," Polym. Intl, 57, 6-10, (2008). PDF

 

64. S. H. Seo, J. H. Park, G. N. Tew, J.-Y. Chang, "Thermotropic Liquid Crystals of 1H-Imidazole Amphiphiles Showing Hexagonal Columnar and Micellar Cubic Phases," Tetrahedron Letters, 48, 6839-6844, (2007). PDF

 

63. N. Beckloff, D. Laube, T. Castro, D. Furgang, S. Park, D. Perlin, D. Clements, H. Tang, R. W. Scott, G. N. Tew, G. Diamond, "Activity of an Antimicrobial Peptide Mimetic Against Planktonic and Biofilm Cultures of Oral Pathogens," Antimicrobial Agents and Chemotherapy, 51, 4125-4132, (2007). PDF

 

62. N. Sanabria-DeLong, S. K. Agrawal, S. R. Bhatia, G. N. Tew, "Impact of Synthetic Technique on PLA-PEO-PLA Physical Hydrogel Properties," Macromolecules, 40, 7864-7873, (2007). PDF

 

61. K. A. Aamer, G. N. Tew, "RAFT Polymerization of a Novel Activated Ester Monomer and Conversion to a Terpyridine-Containing Homopolymer," J. Polym. Sci: Part A: Polym. Chem., 45, 5618-5625, (2007). PDF

 

60. R. Shunmugam, G. N. Tew, “Dialing in Color with Rare Earth Metals: Facile Production of True White Light,” Polym. Adv. Tech., 18, 940-945, (2007). PDF

 

59.  L. Yang, V. D. Gordon, A. Mishra, A. Som, K. R. Purdy, M. A. Davis, G. N. Tew, G. C. L. Wong, “Synthetic Antimicrobial Oligomers Induce a Composition-Dependent Topological Transition in Membranes,” J. Am. Chem. Soc., 129, 12141-12147, (2007). PDF

 

58.  S. K. Agrawal, N. Sanabria-DeLong, P. R. Jemian, G. N. Tew, Bhatia, S. R., “Micro- to Nanoscale Structure of Biocompatibale PLA-PEO-PLA Hydrogels,” Langmuir, 23, 5039-5044, (2007). PDF

 

57.  J. A. Zimberlin, N. Sanabria-DeLong, G. N. Tew, A. J. Crosby, “Cavitation Rheology for Soft Materials,” Soft Matter, 3, 763-767, (2007). PDF

 

56.  G. J. Gabriel, A. Som, A. E. Madkour, T. Eren, G. N. Tew, "Infectious Disease: Connecting Innate Immunity to Biocidal Polymers," Materials Science and Engineering: R: Reports, 57, 28-64, (2007). *Invited article. PDF

 


55.  R. Shunmugam, C. E. Smith, G. N. Tew, "ATRP Synthesis of ABC Lipophilic-Hydrophilic-Fluorophilic Triblock Copolymers," J. Polym. Sci.; Part A: Polym. Chem., 45, 2601-2608, (2007). PDF

54.  K. A. Aamer, G. N. Tew, "Synthesis, Dynamic Light Scattering, and Luminescence Properties of Copolymers Containing Iridium (III) Bisterpyridine in the Side Chain," J. Polym. Sci.; Polym. Chem., 45, 1109-1121, (2007). PDF

53. K. A. Aamer, G. N. Tew, “Supramolecular Polymers Containing Terpyridine -- Metal Complexes in the Side Chain,” Macromolecules, 40, 2737-2744, (2007). PDF

52. M. M. Slutsky, T. V. Jones, G. N. Tew, “Spin System Assignment of Homo-o-Phenylene Ethynylene Oligomers,” J. Org. Chem., 72, 342-347, (2007). PDF

51. A. M. Alb, P. Enohnyaket, M. F. Drenski, R. Shunmugam, G. N. Tew, W. F. Reed, “Quantitative Contrasts in the Copolymerization of Acrylate- and Methacrylate-Based Comonomers,” Macromolecules, 39, 8283-8292, (2006). PDF

50. S.H. Seo, G.N. Tew, J.Y. Chang ,“Lyotropic Columnar Liquid Crystals Based on Polycatenar 1H-imidazole Amphiphiles and Their Assembly into Bundles at the Surface of Silicon,” Soft Matter, 2 (10): 886-891, (2006). PDF

49. G.N. Tew, D. Clements, H.Z. Tang, et al.,“Antimicrobial Activity of an Abiotic Host Defense Peptide Mimic,” Biochimica et Biophysica ACTA-Biomembranes, 1758 (9): 1387-1392, (2006). *Invited article. PDF

48. Y. Ishitsuka, L. Arnt, M. Ratajczek, S. Frey, J. Majewski, K. Kjaer, G. N. Tew, K. Y. C. Lee, “Amphiphilic Poly(Phenylene Ethynylene)s Can Mimic Antimicrobial Peptide Membrane Disordering Effect by Membrane Insertion,” J. Am. Chem. Soc., 128, 13123-13129, (2006) PDF

47. S. H. Seo, J. Y. Chang, G. N. Tew, “Self-Assembled Vesicles from an Amphiphilic ortho-Phenylene Ethynylene Macrocycle,” Angew. Chem. Int. Ed., 45, 7526-7530, (2006). Highlighted with Frontispiece.) PDF

46. S. K. Agrawal, N. Sanabria-DeLong, J. M. Coburn, G. N. Tew, S. R. Bhatia, “Novel Drug Release Profiles from Micellar Solutions of PLA-PEO-PLA Triblock Copolymers,” J. Controlled Release, 112, 64-71, (2006). PDF

45. S. K. Agrawal, N. Sanabria-DeLong, G. N. Tew, S. R. Bhatia, "Rheological Characterization of Biocompatible Associative Polymer Hydrogels with Crystalline and Amorphous Endblocks,” J. Mater. Res., 21, 2118-2125, (2006).PDF

44. K. Nusslein. L. Arnt, J. Rennie, C. Owens, G. N. Tew, “Broad-Spectrum Antibacterial Activity by a Novel Abiogenic Peptide Mimic,” Microbiology, 152, 1913-1918, (2006).PDF

43. H. Tang, R. J. Doerksen, T. V. Jones, M. L. Klein, G. N. Tew, "Biomimetic Facially Amphiphilic Antibacterial Oligomers with Intramolecular Hydrogen Bonding,” Chem. Bio., 13, 427-435, (2006). PDF

42. S. H. Seo, H. Seyler, J. O. Peters, T. V. Jones, T. H. Kim, J. Y. Chang, G. N. Tew, "Liquid Crystalline Order from Ortho-Phenylene Ethynylene Macrocycles,", J. Am. Chem. Soc., 128, 9264-9265, (2006). PDF.

41. T. Kim, L. Arnt, E. Atkins, G. N. Tew, "Self-Assembled Structures with Liquid Crystalline Order in Aqueous Solution by Patterning Meta-Poly(phenylene ethynylene)s," Chem: Eur. J., 12, 2423-2427, (2006). *Highlighted with frontispiece PDF

40. X. Chen, H. Tang, J. Wang, M. A. Even, G. N. Tew, Z. Chen, “Observing a Molecular Knife at Work,” J. Am. Chem. Soc., 128, 2711-2714, (2006). *Selected for "Research Highlights," Nature, 439, 895, (2006). PDF

39. L. Arnt, J. Rennie, S. Linser, R. Willumeit, G. N. Tew, "Membrane Activity of Biomimetic Facially Amphiphilic Antiobiotics," J. Phys. Chem. B., 110, 3527-3532, (2006). PDF

38. N. Sanabria-DeLong, S. Agrawal, S. R. Bhatia, G. N. Tew, “Controlling Hydrogel Properties by Crystallization of Hydrophobic Domains,” Macromolecules, 39, 1308-1310, (2006). PDF

37. T. V. Jones, M. M. Slutsky, R. Laos, T. F. A. de Greef, G. N. Tew, “Solution 1H NMR Confirmation of Folding in Short o-Phenylene Ethynylene Oligomers,” J. Am. Chem. Soc., 127, 17235-17240, (2005). PDF

36. R. Shunmugam, G. N. Tew, “An Efficient Route to Well Characterized Homo, Block, and Statistical Polymers Containing Terpyridine in the Side Chain,” J. Polym. Sci., Polym. Chem., 43, 5831-5843, (2005). PDF

35. R. Shunmugam, G. N. Tew, “Unique Emission from Polymer Based Lanthanide Alloys,” J. Am. Chem. Soc., 127, 13567-13572, (2005). PDF

34. G. N. Tew, N. Sanabria-DeLong, S. Agrawal, S. Bhatia, "New Properties from PLA-PEO-PLA Hydrogels", Soft Matter, 253-258, (2005). *Invited article, Highlighted on the Cover. PDF

33. J. Rennie, L. Arnt, H. Tang, K. Nüsslein, G. N. Tew, “Simple Oligomers as Antimicrobial Peptide Mimics,” J. Industrial Microbiol. Biotechnol., 32, 296-300, (2005). PDF

32. H. Tang, R. Doerksen, G. N. Tew, “Synthesis of Urea Oligomers and Their Antibacterial Activity,” Chem. Comm., 12, 1537-1539, (2005). PDF

31. G. N. Tew, K. Aamer, R. Shunmugam, “Incorporation of Terpyridine into the Side Chain of Copolymers to Create Multi-Functional Materials,” Polymer, 46, 8440-8447, (2005). PDF

30. R. Breitenkamp, L. Arnt, G. N. Tew, “Facially Amphiphilic Phenylene Ethynylenes,” Polym. Adv. Tech., 16, 189-194, (2005). PDF

29. D. Shin, K. Shin, K. Aamer, G. N. Tew, T. P. Russell, J. H. Lee, J. Y. Jho, “A Morphological Study of a Semicrystalline Poly(L-Lactic acid-b-Ethylene oxide-b-L-Lactic acid), Triblock Copolymer,” Macromolecules, 38, 104-109, (2005). PDF

28. M. F. Ilker, K. Nüsslein, G. N. Tew, E. B. Coughlin, “Tuning the Hemolytic and Antibacterial Activities of Amphiphilic Polynorbornene Derivatives,” J. Am. Chem. Soc., 126, 15870-15875, (2004). PDF

27. L. Arnt, K. Nüsslein, G. N. Tew, “Non-Hemolytic Abiogenic Polymers as Antimicrobial Peptide Mimics,” J. Polym. Sci., Polym. Chem., 42, 3860-3864, (2004). Highlighted on the Cover. PDF

26. K. Aamer, G. N. Tew, “Synthesis of Terpyridine-Containing Polymers with Blocky Architectures,” Macromolecules, 37, 1990-1993, (2004). PDF

25. R. B. Breitenkamp, G. N. Tew, “Aggregation of Poly(p-phenylene ethynylene)s Containing Nonpolar and Amine Side Chains,” Macromolecules, 37, 1163-1165, (2004). PDF

24. L. Arnt, G. N. Tew, “Conformational Changes of Facially Amphiphilic Poly(phenylene ethynylene)s in Aqueous Solution,” Macromolecules, 37, 1283-1288, (2004). PDF

23. K. Aamer, H. A. Sardina, S. Bhatia, G. N. Tew, “Rheological Studies of PLLA-PEO-PLLA Triblock Copolymer Hydrogels,” Biomaterials, 25, 1087-1093, (2004). PDF

22. R. A. Blatchly, G. N. Tew, “Theoretical Study of Helix Formation in Substituted Phenylene Ethynylene Oligomers,” J. Org. Chem., 68, 8780-8785, (2003). PDF

21. T.V. Jones, R. A. Blatchly, G. N. Tew, “Synthesis of Alkoxy-Substituted Ortho-Phenylene Ethynylene Oligomers,” Org. Lett., 5, 3297-3299, (2003). PDF

20. L. Arnt, G. N. Tew, “Cationic Facially Amphiphilic Poly(phenylene ethynylene)s Studied at the Air-Water Interface,” Langmuir, 19, 2404-2408, (2003). PDF

19. D. J. Stigers, G. N. Tew, “Poly(3-hydroxyalkanoate)s Functionalize with Carboxylic Acid Groups in the Side Chain,” Biomacromolecules, 4, 193-195, (2003). PDF

18. K. J. Calzia, G. N. Tew, “Methacrylate Polymers Containing Metal Binding Ligands For Use in Supramolecular Materials: Random Copolymers Containing Terpyridines,” Macromolecules, 35, 6090-6093, (2002). PDF

17. L. Arnt, G. N. Tew, "New Poly(phenylene ethynylenes) with Cationic Amphiphilic Structure," J. Am. Chem. Soc., 124, 7664-7665, (2002).PDF

16. D. A. Harrington, H. Benna, G. N. Tew, R. C. Claussen, S. I. Stupp, “Supramolecular Fluorophores for Biological Studies: Phenylene Vinylene - Amino Acid Amphiphiles”, Chem. Bio., 12, 1085-1091, (2005). Highlighted on the Cover. PDF

15. P. V. Braun, P. Osenar, M. Twardowski, G. N. Tew and S. I. Stupp, “Macroscopic Nano-Templating of Semiconductor Films with Hydrogen Bonded Lyotropic Liquid Crystals”, Adv. Funct. Mat., 15, 1745-1750, (2005). PDF

14. R. J. Doerksen, B. Chen, D. Liu, G. N. Tew, W. F. DeGrado, M. L. Klein, “Controlling the Conformation of Arylamides: Computational Studies of Intramolecular Hydrogen Bonds Between Amides and Ethers or Thioethers,” Chem: Eur. J., 10, 5008-5016 (2004). PDF

13. B. M. Rabatic, M. U. Pralle, G. N. Tew, S. I. Stupp, "Nanostructured Semiconductors Templated by Cholesteryl-Oligo(Ethylene Oxide) Amphiphiles", Chem. Mater., 15, 1249-1255, (2003). PDF

12. G. N. Tew, D. Lui, B. Chen, R. Doerksen, J. Kaplan, P. J. Carroll, M. L. Klein, W. F. DeGrado, "De Novo Design of Biomimetic Antimicrobial Polymers", Proc. Natl. Acad. Sci., U.S.A., 99, 5110-5114, (2002). PDF

11. S. I. Stupp, M. U. Pralle, G. N. Tew, E. R. Zubarev: "Self Assembly of Organic Nano-Objects into Functional Materials", MRS Bulletin, 25, 42-48, (2000).PDF

10. M. U. Pralle, K. Urayama, G. N. Tew, D. Neher, G. Wegner, S. I. Stupp, "Piezoelectricity Observed in Polar Supramolecular Materials", Angew. Chem. Int. Ed. 39, 1486-1489, (2000). PDF

9. G. N. Tew, M. U. Pralle, S. I. Stupp, "Supramolecular Materials Containing Electro-Active Groups", Angew. Chem. Int. Ed. 39, 517-521, (2000). PDF

8. G. N. Tew, M. U. Pralle, S. I. Stupp, "Supramolecular Materials From Triblock Rodcoil Molecules Containing Phenylene Vinylene", J. Am. Chem. Soc. 121, 9852-9866, (1999). PDF

7. J. J. Hwang, H.-A. Klok, R. C. Claussen, S. Iyer, G. N. Tew, L.-S. Li, S. I. Stupp, "Self-Assembling Biomaterials", Trans. Soc. for Biomater. 22, 229-231, (1999).

6. S. I. Stupp, M. Keser, G. N. Tew, "Functionalized Supramolecular Materials", Polymer, 39, 4505-4509, (1998).

5. G. N. Tew, L. M. Li, S. I. Stupp, "Polar and Luminescent Supramolecular Films", J. Am. Chem. Soc. 120, 5601-5602, (1998). PDF

4. D. A. Shultz, A. K. Boal, D. J. Driscoll, G. T. Farmer, M. G. Hollomon, J. R. Kitchin, D. B. Miller, G. N. Tew, "Preparation of Paramagnetic Ligands for Coordination-Complexes and Networks With Interesting Magnetic Properties", Mol. Cryst. Liq. Cryst. 305, 303-307, (1997).

3. D. A. Shultz, A. K. Boal, D. J. Driscoll, J. R. Kitchin, G. N. Tew, "Preparation and Characterization of a Bis-Semiquinone: A Bidentate Dianion Biradical", J. Org. Chem. 60, 3578-3579, (1995). PDF

2. D. A. Shultz, G. N. Tew, "Electrochemical Oxidation of a Galvinol-Substituted Alkanethiol", J. Org. Chem. 59, 6159-6160, (1994).


1. D. A. Shultz, D. A. Knox, L. W. Morgan, K. Sandberg, G. N. Tew, "Preparation of meso-Tetra(4-galvinolphenyl)porphyrin-A Building Block for Molecular Magnetic Materials", Tetrahedron Lett. 34, 25, 3975-3977, (1993).

 

PATENTS

  1. Inventors: Tew, G. N., Gabriel, G. J.  Protein Transduction Domains Mimics, WO 2011163637 A2.  Available from: Google Advanced Patent Search. [12/29/11].

  2. Inventors​: DeGrado, W. F., Klein, M. L., Tew, G. N. Facially Amphiphilic Polymers as Anti-infective Agents, European Patent EP2289524 A1. Available from: Google Advanced Patent Search. [3/2/11].

  3. Inventors: DeGrado, W. F., Klein, M. L., Tew, G. N. Facially Amphiphilic Polymers as Anti-Infective Agents, European Patent EP1372674 B1. Available from: Google Advanced Patent Search.[5/25/11].

  4. Inventors: Tew, G. N., Madkour, A. E., Alfred, S. F., King, P. P., Colak, S. Water-Soluble and Water-Insoluble, Ring Opening Metathesis Polymerization Products, Monomers and Related Methods, U. S. Patent US20130072650 A1. Available from: Google Advanced Patent Search. [3/21/13].

  5. Inventors: Sungwook, C., DeGrado, W. F., Klein, M. L., Liu, D., Tew, G. N., Yuan, J. Facially Amphiphilic Polymers and Oligomers and Uses Thereof, European Patent EP 1608313 A2. Available from: Google Advanced Patent Search. [12/28/05].

  6. Inventors: DeGrado, W. F., Klein, M. L., Liu, D., Tew, G. N. Facially Amphiphilic Polyaryl and Polarylalkynyl Polymers and Oligomers and Uses Thereof,  European Patent EP 2468711 A3. Available from: Google Advanced Patent Search. [9/19/02].

  7. Inventors: Bhatia, S., Tew, G. N. Poly (lactic acid) Copolymer Hydrogels and Related Methods of Drug Delivery, WO 2006007402 A2. Available from: Google Advanced Patent Search. [1/19/06].

  8. Inventors: Arnt, L., DeGrado, W. F.,Tew, G. N.  Facially Amphiphilic Polymers and Oligomers, Compositions Thereof, and Use Thereof in Methods of Treating Cancer, European Patent EP2433628A1. Available from: Google Advanced Patent Search. [3/2/12].

  9. Inventors: Tew, G. N., Ilker, F. M., Coughlin, B. E. Amphiphilic Polynorbornene Derivatives and Methods of Using the Same, WO2006021001 A2. Available from: Google Advanced Patent Search. [2/23/06].

  10. Inventors: Tew, G. N., Madkour, A. E., Lienkamp, K., Musante, A. M. Antimicrobial Polymers, WO2010144386 A3. Available from: Google Advanced Patent Search. [5/26/11].

  11. Inventors: DeGrado, W. F., Klein, M. L., Tew, G. N. Facially Amphiphilic Polymers as Anti-Infective Agents, WO2002072007A3. Available from: Google Advanced Patent Search. [5/22/03].

  12. Inventors: DeGrado, W. F., Klein, M. L., Liu, D., Tew, G. N. Facially Amphiphilic Polyaryl and Polyarylalkynyl Polymers and Oligomers and Uses Thereof, WO2005072246 A3, Available from: Google Advanced Patent Search. [6/29/06].

  13. Inventors: Choi, S., DeGrado, W. F., Klein, M. L., Liu, D., Tew, G. N., Yuan, J. Facially Amphiphilic Polymers and Oligomers and Uses Thereof, WO2004082634 A3. Available from: Google Advanced Patent Search. [11/10/05].

  14. Inventors: DeGrado, W. F., Liu, D., Tew, G. N., Klein, M. L., Yuan, J., Choi, S. Facially Amphiphilic Polymers and Oligomers and Uses Thereof, European Patent EP2471527 A3. Available from: Google Advanced Patent Search. [12/12/12].

  15. Inventors: Bhatia, S., Tew, G. N. Poly (lactid acid) Copolymer Hydrogels and Related Methods of Drug Delivery, European Patent EP1765285 A2. Available from: Google Advanced Patent Search. [3/28/07].

  16. Inventors: DeGrado, W. F., Liu, D., Tew, G. N., Klein, M. L., Yuan, J., Choi, S. Facially Amphiphilic Polymers and Oligomers and Uses Thereof, European Patent EP2471526 A3. Available from: Google Advanced Patent Search. [12/12/12].

  17. Inventors: Tew, G. N., Ilker, F. M., Coughlin, B. E.  Amphiphilic Polynorbornene Derivatives and Methods of Using the Same, European Patent EP1793838 A2. Available from: Google Advanced Patent Search. [3/13/07].

  18. Inventors: Tew, G. N., Madkour, A. E., Alfred, S. F., King, P. P., Colak, S. Water-Soluble and Water Insoluble, Ring Opening Metathesis Polymerization Products, Monomers and Related Methods, U. S. Patent US8329927 B2. Available from: Google Advanced Patent Search. [12/11/12].

  19. Inventors: DeGrado, W. F., Liu, D., Tew, G. N., Yuan, J. Facially Amphiphilic Polymers as Anti-infective Agents, European Patent EP1372551 B1. Available from: Google Advanced Patent Search. [9/17/08].

  20. Inventors: Tew, G. N., Shunmugam, R. Terpyridine-substituted Compounds and Related Selective Detection Methods, U. S. Patent US8431406 B2. Available from: Google Advanced Patent Search. [4/30/13].

  21. Inventors: Lienkamp, K., Madkour, A. E., Musante, A. M., Tew, G. N. Antimicrobial Polymers, European Patent EP2440540A2. Available from: Google Advanced Patent Search. [4/18/12].

  22. Inventors: AL-Badri, Z., Russell, T. P., Shunmugam, R., Tew, G. N. Ferromagnetic Block Polymers and Related Methods, U. S. Patent US20110064944A1. Available from: Google Advanced Patent Search. [3/17/11].

Book Chapters

1. S. I. Stupp, G. N. Tew, C. M. Whitaker: Programming Molecules to Form Supramolecular Materials in Hyper-Structured Molecules I: Chemistry, Physics and Applications, Gordon and Breach, H. Sasabe, Eds., invited contribution, 9 (1999).

2. G. N. Tew, S. I. Stupp: Multifunctional Supramolecular Materials in Functional Polymers: Modern Synthetic Methods and Novel Structures, ACS Symp. Ser., A. O. Patil, D. N. Schulz, and B. Novak, Eds., 218 (1998).

3. S. I. Stupp, M. U. Pralle, P. V. Braun, G. N. Tew, P. Osenar, L. S. Li: Controlling Morphology through Self Assembling Supramolecular Materials: A Synthetic Route to Quantum Dots, Proc. of the 4th Inter. Symp. on Quantum Confinement: Nanoscale Materials, Devices, and Systems, Electrochem. Soc., M. Cahay, ed., 11, 3 (1997).

At UMass-Amherst

4. *K. Lienkamp, A. E. Madkour, G. N. Tew, “Antibacterial Peptidomimetics: Polymeric Synthetic Mimics of Antimicrobial Peptides,” in Advances in Polymer Science, A. Abe, H. H. Kausch, M. Moller, H. Pasch, Eds., Vol. 251, 141-172, (2013).

5. S. R. Bhatia, G. N. Tew: PLA-PEO-PLA Hydrogels: Chemical Structure, Self-Assembly and Mechanical Properties in Degradable Polymers and Materials: Principles and Practice, ACS Div of Polym Chem, K. Kemani, C. Scholz, Eds., 114, (2012).

6. *M. Lis, G. N. Tew, 9.16 Polymer-Membrane Interactions in Polymer Science: A Comprehensive Reference, Krzysztof Matyjaszewski and Martin Möller, Eds. Vol. 9, 289-315, (2012).

7. *M. Firat Ilker, G. N. Tew, E. Bryan Coughlin, Amphiphilic Polymers with Potent  Antibacterial Activity, in Antiterrorism and Homeland Defense: Polymers and Materials, J. G. Reynolds, G. E. Lawson, C. J. Koester, Eds. ACS Symp. Ser., No. 980, (2008).

8. *S. K. Agrawal, N. Sanabria-DeLong, K. Aamer, H. A. Sardina, S. R. Bhatia, G. N. Tew, Triblock PLLA-PEO-PLLA Hydrogels: Structure and Mechanical Properties, in Polymeric Drug Delivery II: Polymeric Matrices and Drug Particle Engineering, S. Svenson, Ed. ACS Symp. Ser., 102-119, (2006).

9.  *G. N. Tew, K. Aamer, R. Shunmugam, Novel Block Copolymers with Terpyridine Pendant Groups, in Metal-Containing and Metallo-Supramolecular Polymers and Materials, G.R. Newkome, I. Manners, U.S. Schubert, Eds. ACS Symp. Ser., 126-140, (2006).

10. *K. Aamer, R. Shunmugam, G. N. Tew, Supramolecular Block Copolymers Containing Metal-Ligand Binding Sites: From Synthesis to Properties, in Block Copolymer in Nanoscience, M. Lazzari, S. Lecommandoux, and G. Liu, Eds. Wiley-VCH, 169-189, (2006).

11. *M. M. Slutsky, R. A. Blatchly, G. N. Tew, Foldamers: Nanoscale Shape Control at the Interface between Small Molecules and High Polymers, in Physical Properties of Polymers Handbook, J. E. Marks, Ed. Springer, 699-714, (2006).

12. *N. Sanabria-DeLong, K. A. Aamer, S. K. Agrawal, S. R. Bhatia, G. N. Tew: PLA-PEO-PLA Triblock Copolymers: Synthesis and Thermal Properties, in Degradable Polymers and Materials – Principles and Practice, K. Khemani and C. Scholz, Eds. ACS Symp. Ser., No. 939, (2006).

* denotes where Tew is lead author